Summary
| Production Name | Protein Kinase D2 Rabbit Monoclonal Antibody |
| Description | Recombinant rabbit monoclonal antibody |
| Host | Rabbit |
| Application | WB,IHC,ICC/IF |
| Reactivity | Human,Mouse |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG |
| Clonality | Monoclonal |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt. |
| Purification | Affinity Purification |
Immunogen
| Gene Name | Protein Kinase D2 |
| Alternative Names | PKD2; HSPC187; nPKC-D2 |
| Gene ID | 25865 |
| SwissProt ID | Q9BZL6 |
Application
| Dilution Ratio | WB 1:500-1:2000,IHC 1:50-1:200,ICC/IF 1:100-1:200 |
| Molecular Weight | Calculated MW:97 kDa; Observed MW:105 kDa |
Background
The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Research Area