Summary
Performance
Immunogen
Application
Background
RAB24 is a small GTPase of the Rab subfamily of Ras-related proteins that regulate intracellular protein trafficking (Olkkonen et al., 1993 [PubMed 8126105]).[supplied by OMIM, Aug 2009],function:May be involved in autophagy-related processes.,induction:By extensive retinoic acid treatment, in Ntera-2 teratoma cell line induced to differentiate into post-mitotic neurons (NTN2) (at protein level).,miscellaneous:The unusual Ser-67, instead of a conserved Gln in other family members, is the cause of low GTPase activity. As a result, the predominant nucleotide associated with the protein is GTP.,PTM:Isoprenylation is inefficient compared to other Rab family members.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Only about 20-25% is recovered in the particulate fraction.,subunit:Unlike other Rab family members, does not interact with GDP dissociation inhibitors (GDIs), including ARHGDIA and ARHGDIB.,
Research Area
Cardiovascular; Heart; Autophagy; APG gene products; Cancer; Signal transduction; Autophagy; Metabolism; Pathways and Processes; Metabolism processes; Autophagy and mitophagy; APG gene products
