USP30 Rabbit Polyclonal Antibody($99/20μL)

Summary

Production Name	USP30 Rabbit Polyclonal Antibody
Description	Rabbit polyclonal Antibody
Host	Rabbit
Application	WB,ELISA
Reactivity	Human,Mouse,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Polyclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N.
Purification	Affinity purification

Immunogen

Gene Name	USP30
Alternative Names	USP30; Ubiquitin carboxyl-terminal hydrolase 30; Deubiquitinating enzyme 30; Ubiquitin thioesterase 30; Ubiquitin-specific-processing protease 30; Ub-specific protease 30
Gene ID	84749
SwissProt ID	Q70CQ3

Application

Dilution Ratio	WB 1:500-1:2000,ELISA 1:5000-1:20000
Molecular Weight	60kDa,unspecial bands( 65kDa,105kDa,130kDa)in Hela and HCT116 cell.

Background

USP30, a member of the ubiquitin-specific protease family (see USP1, MIM 603478), is a novel mitochondrial deubiquitinating (DUB) enzyme (Nakamura and Hirose, 2008 [PubMed 18287522]).[supplied by OMIM, Dec 2008],catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:May participate in the maintenance of mitochondrial morphology.,similarity:Belongs to the peptidase C19 family.,tissue specificity:Expressed in skeletal muscle, pancreas, liver and kidney.,

Research Area

Cell Biology; Proteolysis / Ubiquitin; Proteasome / Ubiquitin; Deubiquitination; Signal Transduction; Metabolism; Mitochondrial; Epigenetics and Nuclear Signaling; Ubiquitin & Ubiquitin Like Modifiers; Pathways and Processes; Mitochondrial Metabolism; Mitochondrial markers