Ubiquitin Conjugating Enzyme E2 N Rabbit Monoclonal Antibody

Summary

Production Name	Ubiquitin Conjugating Enzyme E2 N Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,ICC/IF
Reactivity	Human,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification	Affinity Purification

Immunogen

Gene Name	UBE2N
Alternative Names	BLU; HEL-S-71; Ubc13; UbCH ben; UbcH13; UBCHBEN; Ube2n
Gene ID	7334
SwissProt ID	P61088

Application

Dilution Ratio	WB 1:500-1:1000,ICC/IF 1:50-1:200
Molecular Weight	Calculated MW: 17 kDa; Observed MW: 17 kDa

Background

The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. This type of polyubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation.

Research Area

Epigenetics and Nuclear Signaling