Urotensin II Rabbit Polyclonal Antibody($99/20μL)

Summary

Production Name	Urotensin II Rabbit Polyclonal Antibody
Description	Rabbit polyclonal Antibody
Host	Rabbit
Application	WB,ELISA
Reactivity	Human,Monkey

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Polyclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% New type preservative N.
Purification	Affinity purification

Immunogen

Gene Name	UTS2
Alternative Names	UTS2; Urotensin-2; Urotensin II; U-II; UII
Gene ID	10911
SwissProt ID	O95399

Application

Dilution Ratio	WB 1:500-1:2000,ELISA 1:5000-1:20000
Molecular Weight	14kDa

Background

This gene encodes a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide. Transcript variants encoding different preproprotein isoforms have been described for this gene. [provided by RefSeq, Jul 2008],function:Highly potent vasoconstrictor.,similarity:Belongs to the urotensin-2 family.,tissue specificity:Brain specific.,

Research Area

Signal Transduction; Growth Factors/Hormones; Hormones; Cardiovascular; Atherosclerosis; Hypertension; Vasoconstriction; Blood; Blood Pressure regulation; Vasculature