Summary
Performance
Immunogen
Application
Background
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.
Research Area
PI3K-Akt signaling pathway,mTOR signaling pathway,Jak-STAT signaling pathway,Hippo signaling pathway