TNF alpha (9D9) Mouse Monoclonal Antibody-EnkiLife

TNF alpha (9D9) Mouse Monoclonal Antibody

Size1:50μL Price1:$150
Size2:100μL Price2:$280
Size3:200μL Price3:$520
Application:WB,IHC-P
Reactivity:Human,Rat,Mouse
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:TNF SKU: AMM00896 Category: Mouse Monoclonal Antibody Tags: Immunology, Mouse, Unconjugated, WB, IHC, Human, Rat, Mouse

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Summary

Production Name	TNF alpha (9D9) Mouse Monoclonal Antibody
Description	Mouse Monoclonal Antibody
Host	Mouse
Application	WB,IHC-P
Reactivity	Human,Rat,Mouse

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG1
Clonality	Monoclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3.
Purification	Affinity Purification

Immunogen

Gene Name	TNF
Alternative Names	TNF; TNFA; TNFSF2; Tumor necrosis factor; Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a
Gene ID	7124
SwissProt ID	P01375

Application

Dilution Ratio	WB: 1:500-1:1000 IHC: 1:50-1:100
Molecular Weight	Calculated MW: 26 kDa; Observed MW: 17,25 kDa

Background

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.