Caspase 1 Rabbit Monoclonal Antibody

Caspase 1 Rabbit Monoclonal Antibody

Size1:50μL Price1:$158 $99
Size2:100μL Price2:$288 $180
Application:WB,IP
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:CASP1 SKU: AMRe01759 Category: Rabbit Monoclonal Antibody Tags: , , , , , ,

Datasheet

Summary

Production Name

Caspase 1 Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,IP

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purification

 

Immunogen

Gene Name

CASP1

Alternative Names

CASP1; IL1BC; IL1BCE; Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45

Gene ID

834

SwissProt ID

P29466

 

Application

Dilution Ratio

WB: 1:500-1:1000 IP: 1:20

Molecular Weight

Calculated MW: 45 kDa; Observed MW: 45,20 kDa

 

Background

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

 

Research Area

Cell Biology

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