Summary
| Production Name | APPL Rabbit Monoclonal Antibody |
| Description | Recombinant rabbit monoclonal antibody |
| Host | Rabbit |
| Application | WB,IHC,ICC/IF,ICC |
| Reactivity | Human,Mouse,Rat |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG |
| Clonality | Monoclonal |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol. |
| Purification | Affinity Purification |
Immunogen
| Gene Name | APPL |
| Alternative Names | DIP13 alpha; DP13A; KIAA1428; APPL1; Dip13-alpha; Adapter protein containing PH domain; DCC-interacting protein 13-alpha;;Dip13 alpha |
| Gene ID | |
| SwissProt ID | Q9UKG1 |
Application
| Dilution Ratio | WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200 |
| Molecular Weight | Calculated MW: 80 kDa ; Observed MW: 85 kDa |
Background
Multifunctional adapter protein that binds to various membrane receptors, nuclear factors and signaling proteins to regulate many processes, such as cell proliferation, immune response, endosomal trafficking and cell metabolism.Regulates signaling pathway leading to cell proliferation through interaction with RAB5A and subunits of the NuRD/MeCP1 complex.
Research Area