Summary

Performance

Immunogen

Application

Background

Interleukine 6 (IL-6) is a cytokine produced primarily by stimulated monocytes, fibroblasts and epithelial cells. It has a wide variety of biological functions through activating a cellsurface signaling assembly composed of IL6, IL6RA, and the shared signaling receptor gp130. The cytokine plays an essential role in the final differentiation of b-cells into Igsecreting cells, and induces myeloma, plasmacytoma growth, nerve cells differentiations. In addition, IL-6 is an important regulator of acute phase reaction.

Research Area

Immunology

Published Literature

1. Peng C, Fan T, Zhou G, Zhao M, Wang T, Cao T, Zheng J, Guo Z, Liang G, Zhang Z, Guan JS, Wang Y. Targeting neuronal FKBP5 attenuates mechanical allodynia by suppressing NF-κB-mediated neuroinflammation in an NTG-induced chronic migraine mouse model. J Headache Pain. 2026 Jul 22;27(1):246. doi: 10.1186/s10194-026-02460-6. PMID: 42902147.