Summary
| Production Name | CD19 Rabbit Monoclonal Antibody |
| Description | Recombinant rabbit monoclonal antibody |
| Host | Rabbit |
| Application | WB,IHC,ICC/IF,FC,IP |
| Reactivity | Mouse |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG |
| Clonality | Monoclonal |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt. |
| Purification | Affinity Purification |
Immunogen
| Gene Name | CD19 |
| Alternative Names | Differentiation antigen CD19; B-lymphocyte antigen CD19; CD19 antigen |
| Gene ID | 12478 |
| SwissProt ID | P25918 |
Application
| Dilution Ratio | WB 1:500-1:2000,IHC 1:200-1:1000,ICC/IF 1:20-1:50,FC 1:200-1:500,IP 1:20-1:50 |
| Molecular Weight | Calculated MW:60 kDa; Observed MW:60-95 kDa |
Background
Involved in several processes, including B-1 B cell differentiation; positive regulation of phosphatidylinositol 3-kinase activity; and positive regulation of release of sequestered calcium ion into cytosol. Acts upstream of or within B cell receptor signaling pathway. Located in external side of plasma membrane. Is integral component of plasma membrane. Is expressed in liver and spleen. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Orthologous to human CD19 (CD19 molecule). [provided by Alliance of Genome Resources, Apr 2022]
Research Area