KD-Validated Src Recombinant Rabbit Monoclonal Antibody

KD-Validated Src Recombinant Rabbit Monoclonal Antibody

Cat. No.: KVAb00235
Size:20μL Price:$118
Size:50μL Price:$218
Size:100μL Price:$318
Application:WB,FCM,ICC

Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Gene Name:SRC
Category: KO&KD Validated Antibodies Tags: , , , , , , , , , , ,

Summary

Production Name

KD-Validated Src Recombinant Rabbit Monoclonal Antibody

Description

KD-Validated antibody

Host

Rabbit

Application

WB,FCM,ICC

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

Rabbit IgG

Clonality

Rabbit mAb

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Purification

Affinity purification

 

Immunogen

Gene Name

SRC

Alternative Names

SRC; SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase; C-Src; SRC1; ASV; V-Src Avian Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog; Proto-Oncogene Tyrosine-Protein Kinase Src; Proto-Oncogene C-Src; EC 2.7.10.2; P60-Src; Protooncogene SRC, Rous Sarcoma; Tyrosine-Protein Kinase SRC-1; Tyrosine Kinase Pp60c-Src; Pp60c-Src; EC 2.7.10; THC6

Gene ID

6714

SwissProt ID

P12931

 

Application

Dilution Ratio

WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000

Molecular Weight

Calculated MW: 59.8kDa

 

Background

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

 

Research Area

Signal Transduction,Epigenetics and Nuclear Signaling,Cancer,Neuroscience

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