RACK1_MOUSE P68040
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UniProt:P68040
Recommended name：Receptor of activated protein C kinase 1
EC number：
Alternative names：(12-3) (Guanine nucleotide-binding protein subunit beta-2-like 1) (Receptor for activated C kinase) (Receptor of activated protein kinase C 1) (p205)
Cleaved into：Receptor of activated protein C kinase 1, N-terminally processed (Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed)
GeneID：14694
Gene names (primary )：Rack1
Gene names (synonym )：Gnb2-rs1 Gnb2l1
Gene names (ORF )：
Length：317
Mass：35077
Sequence：MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIGTR
Tissue specificity：Strongly and ubiquitously expressed in the embryonic and early postnatal brain. At 11.5 dpc, expressed in a high-dorsal to low-ventral gradient throughout the brain. At 13.5 dpc, most abundant in the telecephalon. At 18.5 dpc, expressed most abundantly in layers 1-4 of the cortex, striatum, hippocampus, dentate gyrus, and specific thalamic nuclei. This expression decreases during postnatal development and is localized in the dentate gyrus, habenula, piriform cortex, paraventricular nucleus of the hypothalamus and supraoptic nucleus of the adult brain. {ECO:0000269|PubMed:16414032, ECO:0000269|PubMed:7968370}.
Induction：
Developmental stage：Expressed throughout embryonic brain development with high levels detected at 11.5 dpc, 13.5 dpc and 18.5 dpc. Also detected at high levels in the adult brain. {ECO:0000269|PubMed:16414032}.
Protein families：WD repeat G protein beta family, Ribosomal protein RACK1 subfamily