RHBD2_MOUSE Q8VEK2
We list detailed information on various proteins on this webpage, which EnkiLife references when developing protein-related products. The protein data is sourced from UniProt, and since UniProt updates its information periodically, the data on our webpage may not always be up-to-date or may contain inaccuracies. If you notice any errors while browsing, we warmly welcome your feedback. Additionally, if you have any suggestions regarding any aspect of our website, please feel free to share them with us. As a token of our appreciation, we will offer a free product or a discount voucher for purchases to scientists who provide feedback. Please contact us at Email: order@enkilife.com; to share your feedback and get your rewards.
UniProt:Q8VEK2
Recommended name：Rhomboid domain-containing protein 2
EC number：
Alternative names：(Rhomboid-like protein 7)
Cleaved into：
GeneID：215160
Gene names (primary )：Rhbdd2
Gene names (synonym )：Rhbdl7
Gene names (ORF )：
Length：361
Mass：39108
Sequence：MAAPGPASRFWCSCPEVPSATFFTALLSLLVSGPRLFLLQPPLAPSGLSLRSEALRNWQVYRLVTYIFVYENPVSLLCGAIIIWRFAGNFERTVGTVRHCFFTLIFTVFSAIIYLSFESVSSLSKLGEVEDARGFTPVAFAMLGVTSVRSRMRRALVFGVVVPSVLVPWLLLCASWLIPQTSFLSNVSGLLIGLSYGLTYCYSLDLSERVALKLDQKFPFSLMRRIPLFKYISGSSAERRAAQSRRLNPAPGSYPTQSCHPHLTPSYPVTQMQHASGQKLASWPPGHMPSLPPYQPASGLCYVQNHFGPNPNASSVYPASAGTSQGVQPPSPISCPGTVYSGALGTPGATGSKESSKVAMP
Tissue specificity：Widely expressed, including in retina and brain (at protein level), as well as in kidney, testis and ovary. Expressed in all layers of the retina, including inner segments of photoreceptor cells and ganglion cells (at protein level). {ECO:0000269|PubMed:23386608}.
Induction：
Developmental stage：In the developing eye, already detected at 10.5 dpc. Expression increases from 12.5 though 18.5 dpc in all retinal cells (at protein level). At P1, expressed in a small number of cells at the level of the ganglion cell layer and in the inner edge of the ventricular zone of the retina. The number of expressing cells increases and, by P8 to P11, entirely occupies the ganglion cell layer and inner nuclear layer. At that stage, not detected in the photoreceptor cell bodies of the outer nuclear layer. At P21, expressed in all nuclear layers of the retina, including cones (at protein level). {ECO:0000269|PubMed:23386608}.
Protein families：Peptidase S54 family