SRY_MOUSE Q05738
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UniProt:Q05738
Recommended name：Sex-determining region Y protein
EC number：
Alternative names：(Testis-determining factor)
Cleaved into：
GeneID：21674
Gene names (primary )：Sry
Gene names (synonym )：Tdf Tdy
Gene names (ORF )：
Length：395
Mass：49494
Sequence：MEGHVKRPMNAFMVWSRGERHKLAQQNPSMQNTEISKQLGCRWKSLTEAEKRPFFQEAQRLKILHREKYPNYKYQPHRRAKVSQRSGILQPAVASTKLYNLLQWDRNPHAITYRQDWSRAAHLYSKNQQSFYWQPVDIPTGHLQQQQQQQQQQQFHNHHQQQQQFYDHHQQQQQQQQQQQQFHDHHQQKQQFHDHHQQQQQFHDHHHHHQEQQFHDHHQQQQQFHDHQQQQQQQQQQQFHDHHQQKQQFHDHHHHQQQQQFHDHQQQQQQFHDHQQQQHQFHDHPQQKQQFHDHPQQQQQFHDHHHQQQQKQQFHDHHQQKQQFHDHHQQKQQFHDHHQQQQQFHDHHQQQQQQQQQQQQQFHDQQLTYLLTADITGEHTPYQEHLSTALWLAVS
Tissue specificity：Expressed in the substantia nigra of the brain (at protein level). Expressed in diencephalon, cortex, the substantia nigra of the midbrain and the medial mammillary bodies of the hypothalamus of male, but not female. {ECO:0000269|PubMed:11085593, ECO:0000269|PubMed:15469996, ECO:0000269|PubMed:16488877}.
Induction：
Developmental stage：Expressed in gonadal somatic pre-Sertoli cells from 10.5 to 11.5 dpc. Expressed in pre-Sertoli cells located centrally in the genital ridge and then later in cells located at the cranial and caudal poles (at protein level). {ECO:0000269|PubMed:11784049, ECO:0000269|PubMed:16904257, ECO:0000269|PubMed:7600978, ECO:0000269|PubMed:7670499}.
Protein families：SRY family