CIP1_MOUSE D3Z3K2
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UniProt:D3Z3K2
Recommended name:E3 ubiquitin-protein ligase CCNB1IP1
EC number:EC 2.3.2.27
Alternative names:(Cyclin-B1-interacting protein 1) (RING-type E3 ubiquitin transferase CCNB1IP1)
Cleaved into:
GeneID:239083
Gene names (primary ):Ccnb1ip1
Gene names (synonym ):Gm288 Hei10 Mei4
Gene names (ORF ):
Length:276
Mass:31386
Sequence:MSLCEDMLLCNYRKCRIKLSGYAWVTACSHIFCDQHGSGEFSRSPAICPACNSTLSGKLDIVRTELSPSEEYKAMVLAGLRPEVVLDISSRALAFWTYQVHQERLYQEYNFSKAENHLKQMEKMYMQQIQSKNIELTSMKGEVISMKKVLEEYKKKFSDISEKLMERNRQYQKLQGLYDSLRLRNITIASQEGSLEPGMIPQSGVFGFPPGNNSKFSLDHIPVGNQGGGDEDVQFRPFFVCSPTAPEPINNFFSFASPSHEAEQQVCSRAFKAKRI
Tissue specificity:Expressed predominantly in the testes and 17 day embryos (corresponding to prophase I in females). Weakly or not expressed in other tissues. {ECO:0000269|PubMed:17784788}.
Induction:
Developmental stage:In spermatocytes, synaptonemal complex-associated Ccnb1ip1 foci are detected by early pachynema and their number peaks during midpachynema. In late-pachytene nuclei, Ccnb1ip1 foci number descrease. At the onset of diplonema, foci are no longer detected (at protein level). {ECO:0000269|PubMed:21779533, ECO:0000269|PubMed:24390283}.
Protein families: