TBATA_MOUSE Q7TSD4
We list detailed information on various proteins on this webpage, which EnkiLife references when developing protein-related products. The protein data is sourced from UniProt, and since UniProt updates its information periodically, the data on our webpage may not always be up-to-date or may contain inaccuracies. If you notice any errors while browsing, we warmly welcome your feedback. Additionally, if you have any suggestions regarding any aspect of our website, please feel free to share them with us. As a token of our appreciation, we will offer a free product or a discount voucher for purchases to scientists who provide feedback. Please contact us at Email: order@enkilife.com; to share your feedback and get your rewards.
UniProt:Q7TSD4
Recommended name：Protein TBATA
EC number：
Alternative names：(Protein SPATIAL) (Stromal protein associated with thymii and lymph node) (Thymus, brain and testes-associated protein)
Cleaved into：
GeneID：65971
Gene names (primary )：Tbata
Gene names (synonym )：Spatial
Gene names (ORF )：
Length：393
Mass：43842
Sequence：MTTEVNQLSEHPLVSPKAEPQPETKPENLPRSHGDVGLQKETVVPGIVDFELIHEELKTTKPQTSQPTPSAYRFGRLSHHSFFSRHHPQPQRVTHIQVTGREDLEHSLPLTTSFQLLQAPGVQPMDLTPSADIAGKPVCVVRDEFSLSALTQPTFLSRCLMGMPTISVPIGDPQSNRNPQLSTSDTWRKKLKDLASRVTVFTKEIQPKPDEQKEEPPLREPPPREQGAKYSAETGRLIPASSQALTRRNRQGQRVHPSSKDGGVQASILQDQELLILELLCQILQTDSLRAIQFWLLYAPSKEKDLALGLLQTAVAQLIPQPLSSIPAEKLWNHLQELQEPQETQEAAYSPSLKKTRSPPLPKTDKPEYIGKAQVLLVHPSEDPEEKTTKAES
Tissue specificity：Expressed in the subcapsular region of the thymus and lymph node (at protein level). Highly expressed in thymic cortical stromal cells and testis. Lower levels found in brain cortex, hippocampus, kidney, cerebellum, skeletal muscle, epididymis and ovary. No expression detected in other lymphoid organs including bone marrow and spleen. Isoform 1 and isoform 2 are expressed predominantly in testis. Isoform 3, isoform 4 and isoform 5 are expressed predominantly in thymus although isoform 3 is also expressed in testis. In the CNS, highly expressed in restricted areas, the cerebellum and hippocampus. {ECO:0000269|PubMed:12711538}.
Induction：Up-regulated in aged mice (4 months of age or older).
Developmental stage：In testis, isoform 1 and isoform 2 are expressed only in the adult from postnatal week 7. Expression is detected in pachytene spermatocytes, increases greatly in round spermatids and is very strong in round/elongating and elongating spermatids. Expression is reduced in condensed spermatids and persists in spermatozoa. Isoform 3 is specifically expressed in round spermatids and is greatly reduced in spermatids under maturation (at protein level). Isoform 7 is detected in the embryo from day 10 while isoform 7 is not detected until day 12. In brain, predominantly expressed by granule cells during cerebellar development. Isoform 1 and isoform 3 are differentially expressed during cerebellar development. {ECO:0000269|PubMed:11196687, ECO:0000269|PubMed:12711538, ECO:0000269|PubMed:17196196, ECO:0000269|PubMed:17961552}.
Protein families：TBATA family