CBR2_MOUSE P08074
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UniProt:P08074
Recommended name:Carbonyl reductase [NADPH] 2
EC number:EC 1.1.1.184
Alternative names:(Adipocyte protein P27) (AP27) (Lung carbonyl reductase) (LCR) (NADPH-dependent carbonyl reductase 2)
Cleaved into:
GeneID:12409
Gene names (primary ):Cbr2
Gene names (synonym ):
Gene names (ORF ):
Length:244
Mass:25958
Sequence:MKLNFSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPGIEPVCVDLGDWDATEKALGGIGPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVFQVSQMVARDMINRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKIRVNSVNPTVVLTDMGKKVSADPEFARKLKERHPLRKFAEVEDVVNSILFLLSDRSASTSGGGILVDAGYLAS
Tissue specificity:Lung (ciliated cells, non-ciliated bronchiolar cells and type-II alveolar pneumocytes). Low expression in adipose tissue > testis = heart > kidney = spleen > brain = liver.
Induction:By glucocorticoids. Activated by fatty acids.
Developmental stage:
Protein families:Short-chain dehydrogenases/reductases (SDR) family