OPALI_MOUSE Q7M750
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UniProt:Q7M750
Recommended name：Opalin
EC number：
Alternative names：(Oligodendrocytic myelin paranodal and inner loop protein) (Transmembrane protein 10)
Cleaved into：
GeneID：226115
Gene names (primary )：Opalin
Gene names (synonym )：Tmem10
Gene names (ORF )：
Length：143
Mass：15833
Sequence：MSFSLNFTLPSNTTSSPVVTSAKATDCGPSIGLAAGIPSLLATALLVALLFTLIQRRRTIDDEPVEETEIPCEISELYDNPKISENPRRSPTHEMNPRGSQEGHIYVKTVSGSEEPLPDTYRPPEELERRRGLWWLVPSLSLE
Tissue specificity：Expressed specifically in oligodendrocytes of the brain. {ECO:0000269|PubMed:17442045, ECO:0000269|PubMed:18439243, ECO:0000269|PubMed:18490449, ECO:0000269|PubMed:30837646}.
Induction：By leukemia inhibitory factor (LIF) and cAMP analogs. Suppressed in the presence of astrocytic or neural-stem-like differentiation factors such as bone morphotic protein (BMP) and fetal calf serum. {ECO:0000269|PubMed:17442045}.
Developmental stage：Expression in the cerebellum increases dramatically after the first postnatal week (PubMed:18490449, PubMed:30837646). Selectively expressed in brain at P21, and not expressed in any other tissues tested including thymus, lung, heart, liver, spleen, kidney and testis. {ECO:0000269|PubMed:18490449, ECO:0000269|PubMed:30837646}.
Protein families：