HEM1_RAT   P13195


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UniProt:P13195

Recommended name:5-aminolevulinate synthase, non-specific, mitochondrial

EC number:EC:2.3.1.37

Alternative names:ALAS-H

Cleaved into:

GeneID:65155

Gene names  (primary ):Alas1

Gene names  (synonym ):

Gene names  (ORF ):

Length:642

Mass:71,021

Sequence:METVVRRCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRTVSTSAAQCQQVKETPPANEKEKTAKAAVQQAPDESQMAQTPDGTQLPPGHPSPSTSQSSGSKCPFLAAQLSQTGSSVFRKASLELQEDVQEMHAVRKEVAQSPVLPSLVNAKRDGEGPSPLLKNFQDIMRKQRPERVSHLLQDNLPKSVSTFQYDHFFEKKIDEKKNDHTYRVFKTVNRRAQIFPMADDYTDSLITKKQVSVWCSNDYLGMSRHPRVCGAVIETVKQHGAGAGGTRNISGTSKFHVELEQELADLHGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVNHLRELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYGASGGGIGDRDGVMPKMDIISGTLGKAFGCVGGYIASTSLLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSNEGRALRRQHQRNVKLMRQMLMDAGLPVIHCPSHIIPVRVADAAKNTEICDELMTRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMNFFLEKLLLTWKRVGLELKPHSSAECNFCRRPLHFEVMSEREKAYFSGMSKMVSAQA

Tissue specificity:Expressed in the liver, kidney, brain and testis. 1

Induction:

Developmental stage:Down-regulated by hemin in the liver and by 6-amino-levulinate (or its methyl ester) in the liver, kidney, heart, testis and brain. 2 s

Protein families:


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