HEM1_RAT P13195
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UniProt:P13195
Recommended name:5-aminolevulinate synthase, non-specific, mitochondrial
EC number:EC:2.3.1.37
Alternative names:ALAS-H
Cleaved into:
GeneID:65155
Gene names (primary ):Alas1
Gene names (synonym ):
Gene names (ORF ):
Length:642
Mass:71,021
Sequence:METVVRRCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRTVSTSAAQCQQVKETPPANEKEKTAKAAVQQAPDESQMAQTPDGTQLPPGHPSPSTSQSSGSKCPFLAAQLSQTGSSVFRKASLELQEDVQEMHAVRKEVAQSPVLPSLVNAKRDGEGPSPLLKNFQDIMRKQRPERVSHLLQDNLPKSVSTFQYDHFFEKKIDEKKNDHTYRVFKTVNRRAQIFPMADDYTDSLITKKQVSVWCSNDYLGMSRHPRVCGAVIETVKQHGAGAGGTRNISGTSKFHVELEQELADLHGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVNHLRELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYGASGGGIGDRDGVMPKMDIISGTLGKAFGCVGGYIASTSLLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSNEGRALRRQHQRNVKLMRQMLMDAGLPVIHCPSHIIPVRVADAAKNTEICDELMTRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMNFFLEKLLLTWKRVGLELKPHSSAECNFCRRPLHFEVMSEREKAYFSGMSKMVSAQA
Tissue specificity:Expressed in the liver, kidney, brain and testis. 1
Induction:
Developmental stage:Down-regulated by hemin in the liver and by 6-amino-levulinate (or its methyl ester) in the liver, kidney, heart, testis and brain. 2 s
Protein families: