ADIG_MOUSE   Q8R400


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UniProt:Q8R400

Recommended name:Adipogenin

EC number:

Alternative names:(Small adipocyte factor 1) (SMAF-1)

Cleaved into:

GeneID:246747

Gene names  (primary ):Adig

Gene names  (synonym ):Smaf1

Gene names  (ORF ):

Length:80

Mass:9362

Sequence:MKYPLVPLVSDLTLSFLVFWLCLPVALLLFLTIVWLHFLLSQESKEDDSDLCFNWEPWSKRPSECGCEETFPGEEDGLHW

Tissue specificity:Selectively expressed in adipose tissue where it is particularly enriched in brown adipose tissue. In adipose tissue, expressed exclusively in adipocytes and not in the stromal-vascular cell population. Expressed at much lower levels in heart, stomach and muscle and barely detected in kidney and lung. {ECO:0000269|PubMed:15567149, ECO:0000269|PubMed:16132694}.

Induction:Induced during adipose conversion of 3T3-L1 cells. Up-regulated in 3T3-L1 adipocytes by troglitazone which stimulates PPARG expression during differentiation. Down-regulated in 3T3-L1 adipocytes exposed to TNF-alpha and to retinoic acid. {ECO:0000269|PubMed:15567149, ECO:0000269|PubMed:16132694}.

Developmental stage:

Protein families:Adipogenin family


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