CASP8_MOUSE O89110
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UniProt:O89110
Recommended name：Caspase-8
EC number：EC 3.4.22.61
Alternative names：(CASP-8)
Cleaved into：Caspase-8 subunit p18; Caspase-8 subunit p10
GeneID：12370
Gene names (primary )：Casp8
Gene names (synonym )：
Gene names (ORF )：
Length：480
Mass：55357
Sequence：MDFQSCLYAIAEELGSEDLAALKFLCLDYIPHKKQETIEDAQKLFLRLREKGMLEEGNLSFLKELLFHISRWDLLVNFLDCNREEMVRELRDPDNAQISPYRVMLFKLSEEVSELELRSFKFLLNNEIPKCKLEDDLSLLEIFVEMEKRTMLAENNLETLKSICDQVNKSLLGKIEDYERSSTERRMSLEGREELPPSVLDEMSLKMAELCDSPREQDSESRTSDKVYQMKNKPRGYCLIINNHDFSKAREDITQLRKMKDRKGTDCDKEALSKTFKELHFEIVSYDDCTANEIHEILEGYQSADHKNKDCFICCILSHGDKGVVYGTDGKEASIYDLTSYFTGSKCPSLSGKPKIFFIQACQGSNFQKGVPDEAGFEQQNHTLEVDSSSHKNYIPDEADFLLGMATVKNCVSYRDPVNGTWYIQSLCQSLRERCPQGDDILSILTGVNYDVSNKDDRRNKGKQMPQPTFTLRKKLFFPP
Tissue specificity：Expressed in a wide variety of tissues. Highest expression in spleen, thymus, lung, liver and kidney. Lower expression in heart, brain, testis and skeletal muscle. {ECO:0000269|PubMed:9654089, ECO:0000269|PubMed:9837723}.
Induction：
Developmental stage：In the embryo, highest expression occurs at day 7. {ECO:0000269|PubMed:9654089, ECO:0000269|PubMed:9837723}.
Protein families：Peptidase C14A family