CCNA2_MOUSE P51943
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UniProt:P51943
Recommended name:Cyclin-A2
EC number:
Alternative names:(Cyclin-A)
Cleaved into:
GeneID:12428
Gene names (primary ):Ccna2
Gene names (synonym ):Ccna Cyca Cyca2
Gene names (ORF ):
Length:422
Mass:47269
Sequence:MPGTSRHSGRDAGSALLSLHQEDQENVNPEKLAPAQQPRAQAVLKAGNVRGPAPQQKLKTRRVAPLKDLPINDEHVTAGPSWKAVSKQPAFTIHVDEAEETQKRPAELKETECEDALAFNAAVSLPGARKPLTPLDYPMDGSFESPHAMDMSIVLEDKPVNVNEVPDYQEDIHTYLREMEVKCKPKVGYMKRQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYSKKQVLRMEHLVLKVLAFDLAAPTVNQFLTQYFLHLQPANCKVESLAMFLGELSLIDADPYLKYLPSLIAGAAFHLALYTVTGQSWPESLAQQTGYTLESLKPCLVDLHQTYLKAPQHAQQSIREKYKHSKYHSVSLLNPPETLSV
Tissue specificity:Ubiquitous (PubMed:8565853). In the testis, expressed in germ cells and in the ovary, in both germline and somatic cells (PubMed:8575639, PubMed:10068472). {ECO:0000269|PubMed:10068472, ECO:0000269|PubMed:8565853, ECO:0000269|PubMed:8575639}.
Induction:
Developmental stage:Accumulates steadily during G2 and is abruptly destroyed at mitosis. Expressed in spermatogonia and is most abundant in preleptotene spermatocytes, cells which will enter the meiotic pathway. {ECO:0000269|PubMed:10068472, ECO:0000269|PubMed:8565853, ECO:0000269|PubMed:8575639}.
Protein families:Cyclin family, Cyclin AB subfamily