IL6RA_MOUSE P22272
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UniProt:P22272
Recommended name：Interleukin-6 receptor subunit alpha
EC number：
Alternative names：(IL-6 receptor subunit alpha) (IL-6R subunit alpha) (IL-6R-alpha) (IL-6RA) (IL-6R 1) (CD antigen CD126)
Cleaved into：Soluble interleukin-6 receptor subunit alpha (sIL6R)
GeneID：16194
Gene names (primary )：Il6ra
Gene names (synonym )：Il6r
Gene names (ORF )：
Length：460
Mass：50455
Sequence：MLTVGCTLLVALLAAPAVALVLGSCRALEVANGTVTSLPGATVTLICPGKEAAGNVTIHWVYSGSQNREWTTTGNTLVLRDVQLSDTGDYLCSLNDHLVGTVPLLVDVPPEEPKLSCFRKNPLVNAICEWRPSSTPSPTTKAVLFAKKINTTNGKSDFQVPCQYSQQLKSFSCQVEILEGDKVYHIVSLCVANSVGSKSSHNEAFHSLKMVQPDPPANLVVSAIPGRPRWLKVSWQHPETWDPSYYLLQFQLRYRPVWSKEFTVLLLPVAQYQCVIHDALRGVKHVVQVRGKEELDLGQWSEWSPEVTGTPWIAEPRTTPAGILWNPTQVSVEDSANHEDQYESSTEATSVLAPVQESSSMSLPTFLVAGGSLAFGLLLCVFIILRLKQKWKSEAEKESKTTSPPPPPYSLGPLKPTFLLVPLLTPHSSGSDNTVNHSCLGVRDAQSPYDNSNRDYLFPR
Tissue specificity：Expressed by dendritic cells. {ECO:0000269|PubMed:27893700}.; [Soluble interleukin-6 receptor subunit alpha]: Detected in the cerebrospinal fluid. {ECO:0000269|PubMed:28402851}.
Induction：[Soluble interleukin-6 receptor subunit alpha]: Levels in the cerebrospinal fluid are increased in obese mice. {ECO:0000269|PubMed:28402851}.
Developmental stage：
Protein families：Type I cytokine receptor family, Type 3 subfamily