SPB6_MOUSE Q60854
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UniProt:Q60854
Recommended name：Serpin B6
EC number：
Alternative names：(Placental thrombin inhibitor) (Proteinase inhibitor 6) (PI-6)
Cleaved into：
GeneID：20719
Gene names (primary )：Serpinb6
Gene names (synonym )：Serpinb6a Spi3
Gene names (ORF )：
Length：378
Mass：42599
Sequence：MDPLQEANGTFALNLLKILGEDSSKNVFLSPMSISSALAMVFMGAKGTTASQMAQALALDKCSGNGGGDVHQGFQSLLTEVNKTGTQYLLRTANRLFGDKTCDLLASFKDSCLKFYEAELEELDFQGATEESRQHINTWVAKKTEDKIKEVLSPGTVNSDTSLVLVNAIYFKGNWEKQFNKEHTREMPFKVSKNEEKPVQMMFKKSTFKMTYIGEIFTKILLLPYVSSELNMIIMLPDEHVELSTVEKEVTYEKFIEWTRLDKMDEEEVEVFLPKFKLEENYNMNDALYKLGMTDAFGGRADFSGMSSKQGLFLSKVVHKAFVEVNEEGTEAAAATAGMMTVRCMRFTPRFCADHPFLFFIHHVKTNGILFCGRFSSP
Tissue specificity：Expressed in the inner ear hair cells, keratinocytes of hair follicles and epidermis in abdominal skin. {ECO:0000269|PubMed:17761692, ECO:0000269|PubMed:20451170}.
Induction：
Developmental stage：At 13.5 dpc, weakly detected in utricle sensory epithelium but not in hair cells. At 16.5 dpc, more prominently detected in crista hair cells. Hair cell expression is sustained in postnatal mice. In cochlea, detected in cochlear hair cells in embryo and in hair cells and the greater epithelial ridge (GER) region in early postnatal age. {ECO:0000269|PubMed:20451170}.
Protein families：Serpin family, Ov-serpin subfamily