RYK_MOUSE Q01887
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UniProt:Q01887
Recommended name：Tyrosine-protein kinase RYK
EC number：EC 2.7.10.1
Alternative names：(Kinase VIK) (Met-related kinase) (NYK-R)
Cleaved into：
GeneID：20187
Gene names (primary )：Ryk
Gene names (synonym )：Mrk
Gene names (ORF )：
Length：594
Mass：66285
Sequence：MRAGRGGVPGSGGLRAPPPPLLLLLLAMLPAAAPRSPALAAAPAGPSVSLYLSEDEVRRLLGLDAELYYVRNDLISHYALSFNLLVPSETNFLHFTWHAKSKVEYKLGFQVDNFVAMGMPQVNISAQGEVPRTLSVFRVELSCTGKVDSEVMILMQLNLTVNSSKNFTVLNFKRRKMCYKKLEEVKTSALDKNTSRTIYDPVHAAPTTSTRVFYISVGVCCAVIFLVAIILAVLHLHSMKRIELDDSISASSSSQGLSQPSTQTTQYLRADTPNNATPITSSSGYPTLRIEKNDLRSVTLLEAKAKVKDIAISRERITLKDVLQEGTFGRIFHGILVDEKDPNKEKQTFVKTVKDQASEVQVTMMLTESCKLRGLHHRNLLPITHVCIEEGEKPMVVLPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHRDLAARNCVIDDTLQVKITDNALSRDLFPMDYHCLGDNENRPVRWMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALGAYV
Tissue specificity：Is detected in all the tissues. Highest levels are seen in the ovary, lung and placenta.
Induction：
Developmental stage：Highest expression at 16 dpc when callosal axons are beginning to cross the midline. At 17 dpc-18 dpc, when the majority of axons are projecting away from the midline, expression is observed but at a lower level. Present on the cell bodies of neurons in cortical layers at 18 dpc. {ECO:0000269|PubMed:16723543, ECO:0000269|PubMed:19000841}.
Protein families：Protein kinase superfamily, Tyr protein kinase family