TSSK4_MOUSE Q9D411
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UniProt:Q9D411
Recommended name：Testis-specific serine/threonine-protein kinase 4
EC number：EC 2.7.11.1
Alternative names：(TSK-4) (TSSK-4) (Testis-specific kinase 4) (EC 2.7.11.1)
Cleaved into：
GeneID：71099
Gene names (primary )：Tssk4
Gene names (synonym )：Tssk5
Gene names (ORF )：
Length：328
Mass：37377
Sequence：MGKGDTSETASATPAYRSVMEEYGYEVGKIIGHGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQVMKVLRHKYLINFYQAIETTSRVYIILELAQGGDVLEWIQRYGACAETLAGKWFSQMALGIAYLHSKGIVHRDLKLENLLLDKRENVKISDFGFAKMVPSSQPVHSSPSYRQMNSLSHLSQTYCGSFAYACPEILLGLPYNPFLSDTWSMGVILYTLVVARLPFDDTNLKKLLRETQKEVTFPANLTISQECKNLILQLLRQSTKRATILDVLRDPWMLKFQPEQPSNEIRLLEAMYQPTSSAKRHQSLEITT
Tissue specificity：[Isoform 1]: Expressed in spermatocytes and mature sperm (at protein level) (PubMed:20729278, PubMed:23054012, PubMed:25361759, PubMed:26940607). Highly expressed in the spleen, heart and testis (PubMed:17927909, PubMed:20729278, PubMed:23054012). Isoform 2, isoform 3, and isoform 4: Expressed at highest level in testis and heart and at low levels in the liver, spleen, kidney, brain and thymus (PubMed:17927909). {ECO:0000269|PubMed:17927909, ECO:0000269|PubMed:20729278, ECO:0000269|PubMed:23054012, ECO:0000269|PubMed:25361759, ECO:0000269|PubMed:26940607}.
Induction：
Developmental stage：Detected throughout spermiogenesis, in round spermatids, elongated spermatids, and mature spermatozoa (PubMed:23054012, PubMed:20729278, PubMed:26940607). Detected at low levels on postnatal day 14, with significantly increased expression on postnatal day 16. Expression levels are unchanged after postnatal day 16 (PubMed:17927909, PubMed:20729278). {ECO:0000269|PubMed:17927909, ECO:0000269|PubMed:20729278, ECO:0000269|PubMed:23054012, ECO:0000269|PubMed:26940607}.
Protein families：Protein kinase superfamily, CAMK Ser/Thr protein kinase family