CSPG5_RAT   Q9ERQ6


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UniProt:Q9ERQ6

Recommended name:Chondroitin sulfate proteoglycan 5

EC number:

Alternative names:

Cleaved into:

GeneID:

Gene names  (primary ):Cspg5

Gene names  (synonym ):Caleb, Ngc

Gene names  (ORF ):

Length:571

Mass:60,959

Sequence:MGRAGGGGPGWGPPPVLLLLGVTLVLTAGAVPAREAGSAIEAEELVRSGLAWESRANDTREEAGLPAAGEDETSWTERGSELAAVGPGVGPEETLEASAAVTGTAWLEADGTGLGGVTAEAGSGDAQTLPATLQAPDEALGSSTMPPAIPEATEASGPPSPTLRDKPSLVPELPKEIPLEVWLNLGGSTPDPQRPEPTFPLQGTLETQPASDIIDIDYFEGLDSEGRGTDMGRFPGSPGTSENHPDTEGETPSWSLLDLYDDFTPFDESDFYPTTSFYDDLEEEEEEEEDKDAVGGGDLEDESDLLLPSQKPGVGPGTGQPTSRWHAVPPQHTLGMVPGGSISLRPRPGDPGKDLATSENGTECRVGFVRHNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHKGMRCESIITDFQVMCVAVGSAALVLLLLFMMTVFFAKKLYLLKTENTKLRRTNKFRTPSELHNDNFSLSTIAEGSHPNVRKLCDTPCVSSPHARALAHCDNIVCQDDPSAPHKIQEALKSRLKEEESFNIQNSMSPKLEGGKGDQDDLEVNCLQNNLT

Tissue specificity:Expressed in cerebral cortex and cerebellum. Expressed in retina (at protein level). 4 s

Induction:Expression starts at 16 dpc in the cerebral cortex and increases to reach a maximum 20 days after birth. Then it decreases till adulthood to be expressed half of the peak level. In the retina, expression reaches a maximum at postnatal day 14 (P14). It starts weakly at 16 dpc in the retinal pigment epithelium (RPE). At P0 it is detected in nerve fiber layer (NFL), ganglion cell layer (GCL), inner plexiform layer (IPL) and RPE. At P7, it becomes intense in the NFL and IPL. At P14, expression becomes intense in the area of outer segments (OS) of the photoreceptor cells as well as in RPE, whereas in the inner layers it becomes gradually fainter. From P21 to P42, it decreases in inner retinal layers. OS and RPE still express, whereas expression in the NFL and IPL decreases (at protein level). 2 Publications

Developmental stage:Up-regulated in nucleus accumbens shell by cocaine administration. 1

Protein families:


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