ERO1A_MOUSE Q8R180
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UniProt:Q8R180
Recommended name：ERO1-like protein alpha
EC number：EC 1.8.4.-
Alternative names：(ERO1-L) (ERO1-L-alpha) (Endoplasmic reticulum oxidoreductase alpha) (Endoplasmic reticulum oxidoreductin-1-like protein) (Oxidoreductin-1-L-alpha)
Cleaved into：
GeneID：50527
Gene names (primary )：Ero1a
Gene names (synonym )：Ero1l
Gene names (ORF )：
Length：464
Mass：54084
Sequence：MGRAWGLLVGLLGVVWLLRLGHGEERRPETAAQRCFCQVSGYLDDCTCDVETIDKFNNYRLFPRLQKLLESDYFRYYKVNLKKPCPFWNDINQCGRRDCAVKPCHSDEVPDGIKSASYKYSEEANRIEECEQAERLGAVDESLSEETQKAVLQWTKHDDSSDSFCEIDDIQSPDAEYVDLLLNPERYTGYKGPDAWRIWSVIYEENCFKPQTIQRPLASGRGKSKENTFYNWLEGLCVEKRAFYRLISGLHASINVHLSARYLLQDTWLEKKWGHNVTEFQQRFDGILTEGEGPRRLRNLYFLYLIELRALSKVLPFFERPDFQLFTGNKVQDAENKALLLEILHEIKSFPLHFDENSFFAGDKNEAHKLKEDFRLHFRNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFSEKLIANMPESGPSYEFQLTRQEIVSLFNAFGRISTSVRELENFRHLLQNVH
Tissue specificity：Widely expressed (at protein level). {ECO:0000269|PubMed:20308425}.
Induction：Stimulated by hypoxia; suggesting that it is regulated via the HIF-pathway. By ER stress in a DDIT3/CHOP-dependent manner. {ECO:0000269|PubMed:12752442, ECO:0000269|PubMed:19752026}.
Developmental stage：
Protein families：EROs family