EFNB3_MOUSE O35393
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UniProt:O35393
Recommended name:Ephrin-B3
EC number:
Alternative names:
Cleaved into:
GeneID:13643
Gene names (primary ):Efnb3
Gene names (synonym ):
Gene names (ORF ):
Length:340
Mass:35885
Sequence:MGAPHFGPGGVQVGALLLLGFAGLVSGLSLEPVYWNSANKRFQAEGGYVLYPQIGDRLDLLCPRARPPGPHSSPSYEFYKLYLVEGAQGRRCEAPPAPNLLLTCDRPDLDLRFTIKFQEYSPNLWGHEFRSHHDYYIIATSDGTREGLESLQGGVCLTRGMKVLLRVGQSPRGGAVPRKPVSEMPMERDRGAAHSAEPGRDTIPGDPSSNATSRGAEGPLPPPSMPAVAGAAGGMALLLLGVAGAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGTADPPFCPHYEKVSGDYGHPVYIVQDGPPQSPPNIYYKV
Tissue specificity:Expressed on lateral floor plate cells, specifically on commissural axon segments that have passed through the floor plate. Expressed in cells of the retinal ganglion cell layer during retinal axon guidance to the optic disk (PubMed:9484836, PubMed:10704386). Expressed in myogenic progenitor cells (PubMed:27446912). {ECO:0000269|PubMed:10704386, ECO:0000269|PubMed:27446912, ECO:0000269|PubMed:9484836}.
Induction:
Developmental stage:Expressed in the floor plate throughout the period of commissural axon pathfinding (PubMed:9484836, PubMed:10704386). In myogenic progenitor cells, highly expressed during early development (11.5 dpc) and progressively repressed as developments proceeds (PubMed:27446912). {ECO:0000269|PubMed:10704386, ECO:0000269|PubMed:27446912, ECO:0000269|PubMed:9484836}.
Protein families:Ephrin family