PPAP_MOUSE   Q8CE08


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UniProt:Q8CE08

Recommended name:Prostatic acid phosphatase

EC number:EC 3.1.3.2

Alternative names:(5'-nucleotidase) (5'-NT) (Acid phosphatase 3) (Ecto-5'-nucleotidase) (Fluoride-resistant acid phosphatase) (FRAP) (Thiamine monophosphatase) (TMPase)

Cleaved into:

GeneID:56318

Gene names  (primary ):Acp3

Gene names  (synonym ):Acpp

Gene names  (ORF ):

Length:381

Mass:43717

Sequence:MRAVPLPLSRTASLSLGFLLLLSLCLDPGQAKELKFVTLVFRHGDRGPIETFPTDPITESSWPQGFGQLTQWGMEQHYELGSYIRKRYGRFLNDTYKHDQIYIRSTDVDRTLMSAMTNLAALFPPEGISIWNPRLLWQPIPVHTVSLSEDRLLYLPFRDCPRFEELKSETLESEEFLKRLHPYKSFLDTLSSLSGFDDQDLFGIWSKVYDPLFCESVHNFTLPSWATEDAMIKLKELSELSLLSLYGIHKQKEKSRLQGGVLVNEILKNMKLATQPQKYKKLVMYSAHDTTVSGLQMALDVYNGVLPPYASCHMMELYHDKGGHFVEMYYRNETQNEPYPLTLPGCTHSCPLEKFAELLDPVISQDWATECMATSSHQGRN

Tissue specificity:Isoform 1 is expressed in salivary gland, thymus and thyroid gland. Isoform 2 is widely expressed in prostate lobes, brain, kidney, liver, lung, muscle, placenta, salivary gland, spleen, thyroid and thymus. Locates to Schwann cells and fibroblasts. Expressed in peptidergic and non-peptidergic nociceptive (pain-sensing) neurons. Preferentially expressed in non-peptidergic doral root ganglia neurons. {ECO:0000269|PubMed:17638863, ECO:0000269|PubMed:18940592, ECO:0000269|PubMed:20084276}.

Induction:

Developmental stage:

Protein families:Histidine acid phosphatase family


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