PROK2_MOUSE Q9QXU7
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UniProt:Q9QXU7
Recommended name:Prokineticin-2
EC number:
Alternative names:(PK2) (Protein Bv8 homolog)
Cleaved into:
GeneID:50501
Gene names (primary ):Prok2
Gene names (synonym ):Bv8
Gene names (ORF ):
Length:128
Mass:14185
Sequence:MGDPRCAPLLLLLLLPLLFTPPAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTPMGQVGDSCHPLTRKSHVANGRQERRRAKRRKRKKEVPFWGRRMHHTCPCLPGLACLRTSFNRFICLARK
Tissue specificity:Expressed in the SCN and among a few other discrete brain areas, including the islands of Calleja, media l preoptic area of the hypothalamus and the shell of the nucleus accumbens. Highly expressed in testis. In the SCN, expression subjected to high amplitude of circadian oscillation.
Induction:Activated by CLOCK and BMAL1 heterodimers and light; inhibited by period genes (PER1, PER2 and PER3) and cryptochrome genes (CRY1 and CRY2).
Developmental stage:Expressed in mid-late pachytene spermatocytes at the stages VII, VIII and IX of the semiferous epithelial cycle.
Protein families:AVIT (prokineticin) family