DAAM1_MOUSE   Q8BPM0


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UniProt:Q8BPM0

Recommended name:Disheveled-associated activator of morphogenesis 1

EC number:

Alternative names:

Cleaved into:

GeneID:208846

Gene names  (primary ):Daam1

Gene names  (synonym ):

Gene names  (ORF ):

Length:1077

Mass:123370

Sequence:MAPRKRGGRGISFIFCCFRNNDHPEITYRLRNDSNFALQTMEPALPMPPVEELDVMFSELVDELDLTDKHREAMFALPAEKKWQIYCSKKKDQEENKGATSWPEFYIDQLNSMAARKSLLALEKEEEEERSKTIESLKTALRTKPMRFVTRFIDLDGLSCILNFLKTMDYETSESRIHTSLIGCIKALMNNSQGRAHVLAHSESINVIAQSLSTENIKTKVAVLEILGAVCLVPGGHKKVLQAMLHYQKYASERTRFQTLINDLDKSTGRYRDEVSLKTAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDFFEMLRNEDELEFAKRFELVHIDTKSATQMFELTRRRLTHSEAYPHFMSILHHCLQMPYKRSGNTVQYWLLLDRIIQQIVIQNDKGQDPDSTPLENFNIKNVVRMLVNENEVKQWKEQAEKMRKEHNELQQKLEKKERECDAKTQEKEEMMQTLNKMKEKLEKETTEHKQVKQQVADLTAQLHELNRRAVCAAVPGGPSPGAPGGPFPSSGLGSLLPPPPPPLLSGGALPPPPPPLPPGGPPPPPGPPPLGGVLPPPGAPVSLTLKKKNIPQPTNALKSFNWSKLPENKLDGTVWTEIDDTKVFKILDLEDLERTFSAYQRQQEFFVNNSKQKEADAIDDTLSSKLKVKELSVIDGRRAQNCNILLSRLKLSNDEIKRAILTMDEQEDLPKDMLEQLLKFVPEKSDIDLLEEHKHELDRMAKADRFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVEAIRSGSEEVFRSRALKQLLEVVLAFGNYMNKGQRGNAYGFKISSLNKIADTKSSIDKNITLLHYLITIVENKYPKVLNLSEELRDIPQAAKVNMTELDKEISTLRSGLKAVETELEYQKSQPPQPGDKFVSVVSQFITLASFSFSDVEDLLAEAKELFTKAVKHFGEEAGKIQPDEFFGIFDQFLQAVAEAKQENENMRKRKEEEERRARLEAQLKEQRERERKVRKAKESSEESGEFDDLVSALRSGEVFDKDLSKLKRNRKRISNQVTDSSRERPITKLNF

Tissue specificity:In early embryogenesis, expressed in embryonic and extraembryonic ectoderm. In later stages of gastrulation, expressed also in somites and ribs and posterior vertebrae of developing skeletal system. During organogenesis, expressed in CNS, PNS, stomach, liver and limb bud. {ECO:0000269|PubMed:15464228, ECO:0000269|PubMed:15533824}.

Induction:

Developmental stage:Detected throughout the myocardial layer of the heart tube. Not expressed in the myocardium at 9.5 dpc but is present in epicardial cells and the pro-epicardial organ. At 10.5 dpc, expressed in the atrial and ventricular myocardia as well as the inter-ventricular septum. Continues to localize to the atrial and ventricular myocardia at 12.5 dpc as well as the ventricular trabeculae. {ECO:0000269|PubMed:26526197}.

Protein families:Formin homology family


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