GOLI_RAT Q6Y290
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UniProt:Q6Y290
Recommended name:E3 ubiquitin-protein ligase RNF130
EC number:EC:2.3.2.27
Alternative names:Goliath homolog (R-goliath) RING finger protein 130
Cleaved into:
GeneID:652955
Gene names (primary ):Rnf130 By Similarity
Gene names (synonym ):
Gene names (ORF ):
Length:419
Mass:46,449
Sequence:MSGAARAGPARLAALALLTCSLWPTRADNASQEYYTALINVTVQEPGRGTPLTFRIDRGRYGLDSPKAEVRGQVLAPLPIHGVADHLGCDPQTRFFVPPNIKQWIALLQRGNCTFKEKISRAAFHNAVAVVIYNNKSKEEPVTMTHPGTGDIIAVMITELRGKDILSYLEKNISVQMTIAVGTRMPPKNFSRGSLVFVSISFIVLMIISSAWLIFYFIQKIRYTNARDRNQRRLGDAAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESYKQNDVVRVLPCKHVFHKSCVDPWLSEHCTCPMCKLNILKALGIVPNLPCTDNVAFDMERLTRTQAVNRRSALGDLANDSSLGLEPLRTSGISPLPQDGELTPRTGEINIAVTKEWFIIASFGLLSALTLCYMIIRATASLNANEVEWF
Tissue specificity:In testis sections, expressed in interstitial tissue and seminiferous tubules. In tubules, expression is mainly in postmeiotic germ cells and to a much lesser extent in Sertoli cells (at protein level). Expressed at high levels in liver, lung, stomach, heart and thymus. 1
Induction:
Developmental stage:Regulated by lutenising hormone (LH) in Leydig cells but not in germ cells. 1
Protein families: