GOLI_RAT   Q6Y290


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UniProt:Q6Y290

Recommended name:E3 ubiquitin-protein ligase RNF130

EC number:EC:2.3.2.27

Alternative names:Goliath homolog (R-goliath) RING finger protein 130

Cleaved into:

GeneID:652955

Gene names  (primary ):Rnf130 By Similarity

Gene names  (synonym ):

Gene names  (ORF ):

Length:419

Mass:46,449

Sequence:MSGAARAGPARLAALALLTCSLWPTRADNASQEYYTALINVTVQEPGRGTPLTFRIDRGRYGLDSPKAEVRGQVLAPLPIHGVADHLGCDPQTRFFVPPNIKQWIALLQRGNCTFKEKISRAAFHNAVAVVIYNNKSKEEPVTMTHPGTGDIIAVMITELRGKDILSYLEKNISVQMTIAVGTRMPPKNFSRGSLVFVSISFIVLMIISSAWLIFYFIQKIRYTNARDRNQRRLGDAAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESYKQNDVVRVLPCKHVFHKSCVDPWLSEHCTCPMCKLNILKALGIVPNLPCTDNVAFDMERLTRTQAVNRRSALGDLANDSSLGLEPLRTSGISPLPQDGELTPRTGEINIAVTKEWFIIASFGLLSALTLCYMIIRATASLNANEVEWF

Tissue specificity:In testis sections, expressed in interstitial tissue and seminiferous tubules. In tubules, expression is mainly in postmeiotic germ cells and to a much lesser extent in Sertoli cells (at protein level). Expressed at high levels in liver, lung, stomach, heart and thymus. 1

Induction:

Developmental stage:Regulated by lutenising hormone (LH) in Leydig cells but not in germ cells. 1

Protein families:


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