IMA8_MOUSE C0LLJ0
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UniProt:C0LLJ0
Recommended name:Importin subunit alpha-8
EC number:
Alternative names:(Karyopherin subunit alpha-7)
Cleaved into:
GeneID:381686
Gene names (primary ):Kpna7
Gene names (synonym ):
Gene names (ORF ):
Length:499
Mass:55458
Sequence:MATSKAPKERLKNYKYRGKEMSLPRQQRIASSLQLRKTRKDEQVLKRRNIDLFSSDMVSQALVKEVNFTLDDIIQAVNSSDPILHFRATRAAREMISQENTPPLNLIIEAGLIPKLVDFLKATPHPKLQFEAAWVLTNIASGTSEQTRAVVKEGAIQPLIELLCSPHLTVSEQAVWALGNIAGDCAEFRDCVISNNAIPHLINLISKGIPITFLRNISWTLSNLCRNKDPYPSESAVRQMLPPLCQLLLHRDNEILADTCWALSYLTKGGKEYIHHVVTTGILPRLVELMTSSELSISIPCLHTIGNIVAGTDEQTQMAIDAGMLKVLGQVLKHPKTSIQVLAAWTMSNVAAGPRHQVEQLLCNLLPILVDLLRNAELKVQKEVVCTVINIATGASQDQLTLLAHSGILEPMLSLLSAPDLEVVIIVLDIISYLLQHIDNLQEKKRLYFQIEKFGGFEKIECLQHHHNISISNSALDIIEKYFCEDGDGDSLPGPGLRV
Tissue specificity:Expressed predominantly in ovary. Isoform 1 is the predominant form. {ECO:0000269|PubMed:20699224}.
Induction:
Developmental stage:Expressed at high levels in germinal vesicle-stage oocytes, as well as in zygotes and 2-cell embryos (at protein level). Drastically down-regulated after the 2-cell stage. {ECO:0000269|PubMed:20699224}.
Protein families:Importin alpha family