RXRA_MOUSE P28700
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UniProt:P28700
Recommended name:Retinoic acid receptor RXR-alpha
EC number:
Alternative names:(Nuclear receptor subfamily 2 group B member 1) (Retinoid X receptor alpha)
Cleaved into:
GeneID:20181
Gene names (primary ):Rxra
Gene names (synonym ):Nr2b1
Gene names (ORF ):
Length:467
Mass:51217
Sequence:MDTKHFLPLDFSTQVNSSSLNSPTGRGSMAVPSLHPSLGPGIGSPLGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFGTGSPQLNSPMNPVSSTEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVEKILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQAT
Tissue specificity:Expressed in macrophages (at protein level). {ECO:0000269|PubMed:25417649, ECO:0000269|PubMed:26463675}.
Induction:Down-regulated by infection with viruses, such as VSV, HSV-1 and MHV68 (PubMed:25417649). Down-regulated by aging (PubMed:26463675). {ECO:0000269|PubMed:25417649, ECO:0000269|PubMed:26463675}.
Developmental stage:
Protein families:Nuclear hormone receptor family, NR2 subfamily