ELMD3_MOUSE   Q91YP6


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UniProt:Q91YP6

Recommended name:ELMO domain-containing protein 3

EC number:

Alternative names:(RNA-binding motif and ELMO domain-containing protein 1)

Cleaved into:

GeneID:232089

Gene names  (primary ):Elmod3

Gene names  (synonym ):Rbed1

Gene names  (ORF ):

Length:381

Mass:42659

Sequence:MSETSCSFFIEKEFQDGQLENVSAGLSSSYKDKGALMAFRGIPISELTNHGILQALTAETNGWQPGVVSEEVLRAQEEWEVVDTIHPDIESGVHCQQPGQLISFNEALEHFQSVDLSSFKKRIQPTIQRTGLAALRHCLFGPPKLHQGLREERDLVLTIAQCGLDSQNPTHGRVLQTIYKKLTGSKFDCALHGDHWEDLGFQGANPATDLRGAGFLALLHLLYLVMDSKTFLMAQEIFRLSHHHIQQFPFCLMSVNITRIAIQALREECLSRECNRRQKVIPVVNSFYAATFLHLARVWRTQQKTILDSGFVLKDLEALAKKSPKRLLKTLDDYLAQVSKGQTSLLEAHKRPGSQGPHSRDLTFTGVCDLQSHSFESAGLI

Tissue specificity:Both isoform 1 and isoform 2 are widely expressed. {ECO:0000269|PubMed:24039609}.

Induction:

Developmental stage:Both isoform 1 and isoform 2 are expressed postnatally in the inner ear. Expression increases from P0 to P30 in both cochlear and vestibular tissues; at all time points, isoform 2 is expressed at several-fold higher levels than isoform 1. At P14, in the organ of Corti, detected along the length of stereocilia of hair cells, particularly in the upper half. Also observed in the microvilli on the apical surface of the hair cells. More abundant in the stereocilia of inner hair cells than in those of outer hair cells (at protein level). In the vestibular sensory epithelium, localizes within the hair cell and supporting cell bodies in the saccule and utricule. Not detected in vestibular hair bundles (at protein level). {ECO:0000269|PubMed:24039609}.

Protein families:


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