ICOS_MOUSE   Q9WVS0


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UniProt:Q9WVS0

Recommended name:Inducible T-cell costimulator

EC number:

Alternative names:(Activation-inducible lymphocyte immunomediatory molecule) (CD28 and CTLA-4-like protein) (CCLP) (CD28-related protein 1) (CRP-1) (CD antigen CD278)

Cleaved into:

GeneID:54167

Gene names  (primary ):Icos

Gene names  (synonym ):Ailim

Gene names  (ORF ):

Length:200

Mass:22709

Sequence:MKPYFCRVFVFCFLIRLLTGEINGSADHRMFSFHNGGVQISCKYPETVQQLKMRLFREREVLCELTKTKGSGNAVSIKNPMLCLYHLSNNSVSFFLNNPDSSQGSYYFCSLSIFDPPPFQERNLSGGYLHIYESQLCCQLKLWLPVGCAAFVVVLLFGCILIIWFSKKKYGSSVHDPNSEYMFMAAVNTNKKSRLAGVTS

Tissue specificity:Expressed on activated T-cells and resting memory T-cells. High expression seen in the thymic medulla and in the germinal centers and T-cell zones of lymph nodes and Peyer patches. Expressed at low levels in the spleen. {ECO:0000269|PubMed:10617205, ECO:0000269|PubMed:10760791, ECO:0000269|PubMed:11006126}.

Induction:

Developmental stage:

Protein families:


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