KLF10_MOUSE   O89091


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UniProt:O89091

Recommended name:Krueppel-like factor 10

EC number:

Alternative names:(GDNF-inducible factor) (Transcription factor GIF) (mGIF) (Transforming growth factor-beta-inducible early growth response protein 1) (TGFB-inducible early growth response protein 1) (TIEG-1)

Cleaved into:

GeneID:21847

Gene names  (primary ):Klf10

Gene names  (synonym ):Gdnfif Tieg Tieg1

Gene names  (ORF ):

Length:479

Mass:51756

Sequence:MLNFGASLQQASEGKMELISEKPREGMHPWDKAEQSDFEAVEALMSMSCDWKSHFKKYLENRPVTPVSDTSEDDSLLPGTPDLQTVPAFCLTPPYSPSDFEPSQGSNLTASAPSTGHFKSFSDAAKPPGATPFKEEEKNPLAAPPLPKAQATSVIRHTADAQLCNHQSCPVKAASILNYQDNSFRRRTHGNVEATRKNIPCAAVSPNRSKPEPSTVSDGDEKAGAALYDFAVPSSETVICRSQPAPSSPVQKSVLVSSPTVSTGGVPPLPVICQMVPLPANNSLVSTVVPSTPPSQPPAVCSPVLFMGTQVPEGTVVFVVPQPVVQSPRPPVVSPSGTRLSPIAPAPGFSPSAARVTPQIDSSRVRSHICSHPGCGKTYFKSSHLKAHVRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPASAQ

Tissue specificity:

Induction:By TGF-beta and GDNF. Expressed in a circadian manner in the liver with a high at ZT14-18 and a low at ZT2 (at protein level). Expressed in a circadian manner in the bone, kidney and skeletal muscle. Up-regulated in response to glucose. {ECO:0000269|PubMed:20070857, ECO:0000269|PubMed:20385766, ECO:0000269|PubMed:9348334}.

Developmental stage:

Protein families:Sp1 C2H2-type zinc-finger protein family


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