ACVR1_MOUSE P37172
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UniProt:P37172
Recommended name：Activin receptor type-1
EC number：EC 2.7.11.30
Alternative names：(Activin receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I) (TSK-7L)
Cleaved into：
GeneID：11477
Gene names (primary )：Acvr1
Gene names (synonym )：Acvrlk2 Tgfb1
Gene names (ORF )：
Length：509
Mass：57226
Sequence：MVDGVMILPVLMMMAFPSPSVEDEKPKVNQKLYMCVCEGLSCGNEDHCEGQQCFSSLSINDGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNFHLEVGLIILSVVFAVCLLACILGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTLAELLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKSAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKIDNSLDKLKTDC
Tissue specificity：Expressed in normal parenchymal cells, endothelial cells, fibroblasts and tumor-derived epithelial cells.
Induction：
Developmental stage：Highly expressed in the node and midline and weakly expressed in 8.5 dpc embryos and in the lateral plate mesoderm. {ECO:0000269|PubMed:15531373}.
Protein families：Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily