RSAD2_MOUSE Q8CBB9
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UniProt:Q8CBB9
Recommended name:Radical S-adenosyl methionine domain-containing protein 2
EC number:
Alternative names:(Viperin) (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible)
Cleaved into:
GeneID:58185
Gene names (primary ):Rsad2
Gene names (synonym ):Vig1
Gene names (ORF ):
Length:362
Mass:41524
Sequence:MGMLVPTALAARLLSLFQQQLGSLWSGLAILFCWLRIALGWLDPGKEQPQVRGEPEDTQETQEDGNSTQPTTPVSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKQAGLEKINFSGGEPFLQDRGEYLGKLVRFCKEELALPSVSIVSNGSLIRERWFKDYGEYLDILAISCDSFDEQVNALIGRGQGKKNHVENLQKLRRWCRDYKVAFKINSVINRFNVDEDMNEHIKALSPVRWKVFQCLLIEGENSGEDALREAERFLISNEEFETFLERHKEVSCLVPESNQKMKDSYLILDEYMRFLNCTGGRKDPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYVWSKADLKLDW
Tissue specificity:Expressed at higher levels in atherosclerotic arteries than in normal arteries. {ECO:0000269|PubMed:15890971}.
Induction:By interferon type I, type II and LPS. Induced by infection with Vesicular stomatitis virus and pseudorabies virus in dendritic cells, presumably through type I interferon pathway. {ECO:0000269|PubMed:11038379, ECO:0000269|PubMed:16849320}.
Developmental stage:
Protein families:Radical SAM superfamily, RSAD2 family