S6A13_MOUSE P31649
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UniProt:P31649
Recommended name：Sodium- and chloride-dependent GABA transporter 2
EC number：
Alternative names：(GAT-2) (Sodium- and chloride-dependent GABA transporter 3) (GAT-3) (Solute carrier family 6 member 13)
Cleaved into：
GeneID：14412
Gene names (primary )：Slc6a13
Gene names (synonym )：Gabt2 Gabt3 Gat-3 Gat2 Gat3
Gene names (ORF )：
Length：602
Mass：68285
Sequence：MENRASGTTSNGETKPVCPAMEKVEEDGTLEREHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQYTNQGGITAWRRICPIFEGIGYASQMIVSLLNVYYIVVLAWALFYLFSSFTTDLPWGSCSHEWNTENCVEFQKANDSMNVTSENATSPVIEFWERRVLKLSDGIQHLGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCIALCILNSSTSFMAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPRVFRKKNRREVLILIVSVISFFIGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGAGRFYDNIEDMIGYKPWPLIKYCWLFFTPAVCLATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMICIPAWSIYKLRTLKGPLRERLRQLVCPAEDLPQKNQPEPTAPATPMTSLLRLTELESNC
Tissue specificity：Expressed at high levels in liver, followed by kidney and leptomeninges, and very low levels in the cerebellum (at protein level).In the brain, detected in some blood vessels (at protein level). In the kidney, expressed in the cortex, including parts of the proximal tubules, but not in the medulla (at protein level). In the liver, highest expression in periportal hepatocytes, with highest density at the vascular side (at protein level). Also detected at low levels in other organs, including skeletal muscle. {ECO:0000269|PubMed:22896705}.
Induction：
Developmental stage：Abundant in neonatal brain, but not in adult brain.
Protein families：Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A13 subfamily