VSX1_MOUSE   Q91V10


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UniProt:Q91V10

Recommended name:Visual system homeobox 1

EC number:

Alternative names:(Homeodomain protein RINX) (Retinal inner nuclear layer homeobox protein) (Transcription factor VSX1)

Cleaved into:

GeneID:114889

Gene names  (primary ):Vsx1

Gene names  (synonym ):Rinx

Gene names  (ORF ):

Length:363

Mass:38755

Sequence:MTGRDGLSDARSRSRALAPGCPPTGSRLRSFAINDLLGLEADLPTPAEPGLRSNSGDPAEAIGSGPGPGPGLCGSCPARGALPLGLGLLCGFGAQPPSAAAAARARCLLLADLRLLPSAGPEPAVAQGPVHPPPALGSQQRSESVSTSDGDSPSEEKNDPKMSLILGKRKKRRHRTVFTAHQLEELEKAFGEAHYPDVYAREMLAAKTELPEDRIQVWFQNRRAKWRKREKRWGGSSVMAEYGLYGAMVRHCIPLPDSVLNSADSLQGSCAPWLLGMHKKSTGMRKPESEDKLAGLWEFDHLKKGANKDEDGPERGPDETTQNPENSLEDVAIDLSSSSRQETKKMPPGSSTQLPQPPQVGAS

Tissue specificity:Expressed in the postnatal retina (at protein level) (PubMed:17919464). In the adult, expressed exclusively in the cells of the neural retina with expression restricted to postnatal cone bipolar interneurons (PubMed:15838724). {ECO:0000269|PubMed:15838724, ECO:0000269|PubMed:17919464}.

Induction:

Developmental stage:Expressed at P5, solely within the inner nuclear layer (INL) of the central neuroretina. By days P6 and P7, expression expands peripherally during neurogenesis. By P12, expression is restricted to the outer margin of the INL and reaches the outer periphery of the neuroretina.

Protein families:Paired homeobox family


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