PCAT1_MOUSE Q3TFD2
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UniProt:Q3TFD2
Recommended name：Lysophosphatidylcholine acyltransferase 1
EC number：EC 2.3.1.23
Alternative names：(LPC acyltransferase 1) (LPCAT-1) (LysoPC acyltransferase 1) (mLPCAT1) (1-acylglycerol-3-phosphate O-acyltransferase) (1-acylglycerophosphocholine O-acyltransferase) (1-alkenylglycerophosphocholine O-acyltransferase) (1-alkylglycerophosphocholine O-acetyltransferase) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 2)
Cleaved into：
GeneID：210992
Gene names (primary )：Lpcat1
Gene names (synonym )：Aytl2
Gene names (ORF )：
Length：534
Mass：59744
Sequence：MRLRGRGPRAAPSSSSGAGDARRLAPPGRNPFVHELRLSALQKAQVAFMTLTLFPIRLLFAAFMMLLAWPFALLASLGPPDKEPEQPLALWRKVVDFLLKAIMRTMWFAGGFHRVAVKGRQALPTEAAILTLAPHSSYFDAIPVTMTMSSIVMKAESRDIPIWGTLIRYIRPVFVSRSDQDSRRKTVEEIKRRAQSNGKWPQIMIFPEGTCTNRTCLITFKPGAFIPGVPVQPVVLRYPNKLDTITWTWQGPGALKILWLTLCQFQNQVEIEFLPVYCPSEEEKRNPALYASNVRRVMAKALGVSVTDYTFEDCQLALAEGQLRLPADTCLLEFARLVRGLGLKPENLEKDLDKYSESARMKRGEKIRLPEFAAYLEVPVSDALEDMFSLFDESGGGEIDLREYVVALSVVCRPSQTLATIQLAFKMYGSPEDGSIDEANLSCILKTALGVSELTVTDLFQAIDQEDKGRITFDDFCGFAEMYPDYAEDYLYPDQTHFDSCAQTPPAPTPNGFCIDFSPENSDFGRKNSCKKAD
Tissue specificity：Predominantly expressed in lung where it is enriched in alveolar type II cells. Expressed at lower levels in spleen and brain. Also detected in erythroleukemic cells and reticulocytes. Weakly or not expressed in other tissues. {ECO:0000269|PubMed:16704971, ECO:0000269|PubMed:16864775, ECO:0000269|PubMed:18156367}.
Induction：Constitutively expressed. Not induced by inflammatory stimulation. {ECO:0000269|PubMed:18285344}.
Developmental stage：Expression increases steadily throughout embryogenesis and decreases slightly in the adult. {ECO:0000269|PubMed:16864775}.
Protein families：1-acyl-sn-glycerol-3-phosphate acyltransferase family