SPTC2_RAT Q3B7D2
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UniProt:Q3B7D2
Recommended name：Serine palmitoyltransferase 2 Curated
EC number：EC:2.3.1.50
Alternative names：Long chain base biosynthesis protein 2 (LCB 2) Serine-palmitoyl-CoA transferase 2 (SPT 2)
Cleaved into：
GeneID：366697
Gene names (primary )：Sptlc2
Gene names (synonym )：Lcb2, Pomt2 Imported
Gene names (ORF )：
Length：560
Mass：62,962
Sequence：MRPEPGGCCCRRPMRANGCVKNGEVRNGYLRSSTATIAAAGQIHHITENGGLYKRPFNEAFEETPMLVAVLTYVGYGVLTLFGYLRDFLRHWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGAKVDIMERQSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAEVLKTYGAGVCSTRQEIGNLDKHEELEKLVARFLGVEAALTYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVDYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSMSPPVMEQIITSMKCIMGQDGTSLGKECIQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKYSRHRPLPLLDRPFDETTYEETED
Tissue specificity：Expressed in astrocytes. 1
Induction：
Developmental stage：Expression in increased by palmitate at protein level but not mRNA level (PubMed:21994399). Expression is down-regulated by microRNA miR-9, miR29a and miR-29b-1 (at protein level) (PubMed:21994399). 1
Protein families：