SELT_MOUSE P62342
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UniProt:P62342
Recommended name：Thioredoxin reductase-like selenoprotein T
EC number：EC 1.8.1.9
Alternative names：(SelT) (EC 1.8.1.9)
Cleaved into：
GeneID：69227
Gene names (primary )：Selenot
Gene names (synonym )：Selt
Gene names (ORF )：
Length：195
Mass：22292
Sequence：MRLLLLLLVAASAVVRSEASANLGGVPSKRLKMQYATGPLLKFQICVSUGYRRVFEEYMRVISQRYPDIRIEGENYLPQPIYRHIASFLSVFKLVLIGLIIVGKDPFAFFGMQAPSIWQWGQENKVYACMMVFFLSNMIENQCMSTGAFEITLNDVPVWSKLESGHLPSMQQLVQILDNEMKLNVHMDSIPHHRS
Tissue specificity：Ubiquitous. Highly expressed in the endocrine pancreas (PubMed:23913443). Expressed at low levels in the adult brain (PubMed:26866473). {ECO:0000269|PubMed:23913443, ECO:0000269|PubMed:26866473}.
Induction：Rapidly induced by ADCYAP1/PACAP neuropeptide (PubMed:23913443). In striatum neurons and astrocytes, induced by Parkinson disease-inducing neurotoxins such as 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) or rotenone (PubMed:26866473). {ECO:0000269|PubMed:23913443, ECO:0000269|PubMed:26866473}.
Developmental stage：
Protein families：SelWTH family, Selenoprotein T subfamily