MTMR2_MOUSE Q9Z2D1
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UniProt:Q9Z2D1
Recommended name：Myotubularin-related protein 2
EC number：EC 3.1.3.95
Alternative names：(Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)
Cleaved into：
GeneID：77116
Gene names (primary )：Mtmr2
Gene names (synonym )：
Gene names (ORF )：
Length：643
Mass：73232
Sequence：MEKSSSCESLGAQLPAARLPSEDSLSSASTSHSENSVHTKSASAISSDSISTSADNFSPDLRVLREANKLAEMEEPALLPGENIKDMAKDVTYICPFTGAVRGTLTVTSYRLYFKSMERDPPFVLDASLGVISRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNGLPLFAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATVTRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPTIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKKTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHSRYKELLAKRAELQRKVEELQREISNRSTSSSERASSPAQCVTPVQTVV
Tissue specificity：Expressed in sciatic nerve and in Schwann cells (at protein level) (PubMed:16399794, PubMed:23297362). Detected in adult dorsal root ganglia, neurons of the central nervous system, motor neurons, cell soma and neurites of sensory neurons, olfactory bulb, cerebellum and hippocampus (PubMed:12045210). {ECO:0000269|PubMed:12045210, ECO:0000269|PubMed:16399794, ECO:0000269|PubMed:23297362}.
Induction：
Developmental stage：In 16.5 dpc embryos, expressed in forebrain, dorsal root ganglia, trigeminal ganglia, kidney, adrenal gland and lung. {ECO:0000269|PubMed:12045210}.
Protein families：Protein-tyrosine phosphatase family, Non-receptor class myotubularin subfamily