RNF6_MOUSE Q9DBU5
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UniProt:Q9DBU5
Recommended name:E3 ubiquitin-protein ligase RNF6
EC number:EC 2.3.2.27
Alternative names:(RING-type E3 ubiquitin transferase RNF6) (RLIM-like protein)
Cleaved into:
GeneID:74132
Gene names (primary ):Rnf6
Gene names (synonym ):
Gene names (ORF ):
Length:667
Mass:74091
Sequence:MDPSRSRSGGSGEESSFQENERRWQQERLHREEAYYQFINELSDEDYRLMRDHNLLGTPGEITSEELQQRLERAKEQLASQPGSDSAASDGDSESLRAHSDEDSLLRWLNTFRRTGNVTRSGQNGNQSWRAVSRTNPNSGEFGFSLEIHINPDNRGSEMHGEDSTDIPLSGVNREHRQQRPSSPVARRTRSQTSMSSSGPRGRRGARRQGSVQGSFATLGRLRNGIGVALGVPRVSAPRTNVINSHTNQSDGSTLRQGGRQRFGAAHIWENGARSNVTVRNTNQRLEPIRLRPAFSSRSRSPIQRQNGTVHHNSQRQGRPVQQTGRNRSVRHRGVTRVFLEQGREHRGTDYTPLSNSRLVSRITVEEGESSRSSAATQRHPAITLDLQVRRIRPGETRDRDSIANRTRSRAGLAESTVESTSGGFHRTISHLERSGVRTYVSTITVPLRRISENDVVEPSSVALRSILRQIMTGFGELSSLMEVEPASENQSNGQRLPEVYLELSNGDAADDSGQHGRASSQASQAQDGAEMLAVREPAPPQARPSGSRSRRQLGRADSVVEAGTLPILRLAHFFLLNEGDDDPIRGLTKEQIDNLSTRSYEQDGVDSELGKVCSVCISDYVAGNKLRQLPCLHEFHIHCIDRWLSENCTCPVCRRPVLEFGATSSG
Tissue specificity:Widely expressed with higher expression in the testis in both germ cells and Sertoli cells. {ECO:0000269|PubMed:11971979}.
Induction:
Developmental stage:Expressed in the floor plate and ventral portions of the developing neural tube of 12.5 dpc to 13 dpc mouse embryos. Found in developing neuronal projections (at protein level). {ECO:0000269|PubMed:16204183}.
Protein families:RNF12 family