NLRP6_RAT Q63035
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UniProt:Q63035
Recommended name：NACHT, LRR and PYD domains-containing protein 6 Curated
EC number：
Alternative names：
Cleaved into：
GeneID：
Gene names (primary )：Nlrp6
Gene names (synonym )：Nalp6 1 Publication, Navr, Pypaf5 1 Publication
Gene names (ORF )：
Length：881
Mass：98,324
Sequence：MDAAGASCSSSEAVARELLLAALQDLSQEQLKRFRHKLRDAPLDGRSIPWGRLEHSDAVDLTDKLIEFYAPEPAVDVTRKILKKADIRDVSLRLKEQQLQRLGSSSALLTVSEYKKKYREHVLRQHAKVKERNARSVKINKRFTKLLIAPGSGAGEDELLGTSGEPEPERARRSDTHTFNRLFRGNDDEGPRPLTVVLQGPAGIGKTMAAKKILYDWAGGKLYHSQVDFAFFMPCGELLERPGTRSLADLILEQCPDRTAPVRRILAQPHRLLFILDGADELPTLAAPEATPCRDPFEATSGLRVLSGLLSQELLPSARLLVTSRNATLGRLQGRLCSPQCAEVRGFSDKDKKKYFFKFFRDERKAERAYRFVKENETLYALCFVPFVCWIVCTVLLQQMELGRDLSRTSKTTTSVYLLFITSMLKSAGTNGPRVQGELRMLCRLAREGILKHQAQFSEKDLERLKLQGSQVQTMFLSKKELPGVLETVVTYQFIDQSFQEFLAALSYLLDAEGAPGNSAGSVQMLVNSDAGLRGHLALTTRFLFGLLSTERIRDIGNHFGCVVPGRVKQDTLRWVQGQSQPKVATVGAEKKDELKDEEAEEEEEEEEEEEEELNFGLELLYCLYETQEDDFVRQALSSLPEMVLERVRLTRMDLEVLSYCVQCCPDGQALRLVSCGLVAAKEKKKKKKSFMNRLKGSQSTGKQPPASLLRPLCEAMITQQCGLSILTLSHCKLPDAVCRDLSEALKVAPSLRELGLLQNRLTEAGLRLLSQGLAWPKCKVQTLRIQMPGLQEVIHYLVIVLQQSPVLTTLDLSGCQLPGTVVEPLCSALKHPKCGLKTLSLTSVELTENPLRELQAVKTLKPDLAIIHSKLGTHPQPLKG
Tissue specificity：Detected in several tissues (PubMed:7489366). Expressed in renal epithelial cells in medullary thick ascending limb of Henle, as well as in salivary gland apical epithelium (at protein level). Isoform 1 is widely expressed. Isoform 2 is primarily expressed in kidney (at protein level) (PubMed:18413781). 2 s
Induction：
Developmental stage：Strongly up-regulated in the intestine in late gestation. 1
Protein families：NLRP family