CLM3_MOUSE Q6SJQ5
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UniProt:Q6SJQ5
Recommended name：CMRF35-like molecule 3
EC number：
Alternative names：(CLM-3) (CD300 antigen-like family member H) (CD300 molecule-like family member D3)
Cleaved into：
GeneID：382551
Gene names (primary )：Cd300ld3
Gene names (synonym )：Cd300lh Clm3 Lmir7
Gene names (ORF )：
Length：245
Mass：27312
Sequence：MWQFPALLFLFLPGCCTAQDPVTGPEEVSGQEQGSLTVQCRYDSGWKDYKKYWCRGAYWKSCEILVETDASEQLVKENRVSIRDDQTDFIFTVTMEDLRMSDADIYWCGITKAGTDPMFKVNVNIDPEISTTIMTTTATVLPSTVLTSTVLTSTVLTPTTPTTESIGTENIGQVTQNSLFIWSLLSSISFLLMVFVVVPLLLSMLSAVLWVNRPQRHYGGGEIGLVETHRSDALDGEKHFPGDEK
Tissue specificity：Highly expressed in bone marrow-derived mast cells and macrophages, peripheral blood monocytes and CD11c+ cells, with weaker expression detected in CD11b cells in bone marrow and peripheral blood. Not detected in B220+ cells in bone marrow or spleen, in Thy-1.2+ or CD3+ cells in peripheral blood, spleen or thymus, or in NK1.1+ cells in spleen (at protein level). Widely expressed in various tissues including heart, liver, spleen, lung, kidney, brain, bone marrow, thymus, axillary lymph node and mesenteric lymph node. Highly expressed in macrophage cell lines J774.1 and RAW 264.7 and in mast cell line MC/9. Weak expression detected in B-lineage cell lines WEHI-231 and A20 and in dendritic cell line DC2.4. Not detected in other myeloid cell lines or T-lineage cell lines. {ECO:0000269|PubMed:20817736, ECO:0000269|PubMed:21940676}.
Induction：Down-regulated in macrophages by single-stranded CpG oligodeoxynucleotide stimulation. {ECO:0000269|PubMed:21940676}.
Developmental stage：
Protein families：CD300 family